Frederick Sanger & Colleagues Conduct the First Whole Genome Shotgun Sequence


In 1982 British biochemist Frederick Sanger and colleagues sequenced the entire genome of bacteriophage lambda using a random shotgun technique. This was the first whole genome shotgun (WGS) sequence.

Sanger, et alNucleotide Sequence of Bacteriophage Lambda,” J. Mol. Biol. 162 (1982) 729-73.

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